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Home / Primary Antibodies / IHC Antibodies

PE/TR Anti-Human CD279/PD-1 Antibody[J116]

SKU : BHA10327462

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1129P
Background	Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Categories	Primary Antibodies;Primary Antibodies///Flow Cytomerty(FACS)
Clonality	Monoclonal
Host	Mouse
Isotype	Mouse IgG1, k
Reactivity	Human
Synonyms	PD-1, Programmed Death-1

Swissprot	Q15116
Accession Number	5133
Gene Id	5133
Clone No	J116

Buffer	PBS with 0.05% Proclin300, 1% BSA
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM

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SKU	Supplier No.	Size	Your price	Quantity
BHA10327462	E-AB-F1129P	20Tests	$85		Add to Cart
BHA10327462	E-AB-F1129P	50Tests	$130		Add to Cart
BHA10327462	E-AB-F1129P	100Tests	$220		Add to Cart
BHA10327462	E-AB-F1129P	200Tests	$330		Add to Cart

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