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Home / Primary Antibodies / IHC Antibodies

NKX3-1 Antibody

SKU : BHA10557729

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA143729
Alternative Names	Homeobox protein Nkx-3.1; NKX31; NKX3A;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.Cai Bowen, Cancer Res., Jan 2007; 67: 455 - 464. Xiang Li, Mol. Cell. Biol., Apr 2006; 26: 3008 - 3017. Ekatherine Asatiani, Cancer Res., Feb 2005; 65: 1164 - 1173. Carlise R. Bethel, Cancer Res., Nov 2006; 66: 10683 - 10690.
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human NKX3., Synthesized peptide derived from N-terminal of Human NKX3.
Raised In	Rabbit
Reactivity	Human, Human
Regulatory	RUO
Relevance	Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. Cai Bowen, Cancer Res., Jan 2007; 67: 455 - 464. Xiang Li, Mol. Cell. Biol., Apr 2006; 26: 3008 - 3017. Ekatherine Asatiani, Cancer Res., Feb 2005; 65: 1164 - 1173. Carlise R. Bethel, Cancer Res., Nov 2006; 66: 10683 - 10690.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total NKX3.1 protein.
Subcellular Location	Nucleus

Uniprot	Q99801, Q99801
Database Links	HGNC:7838 OMIM:602041 KEGG:hsa:4824 STRING:9606.ENSP00000370253 UniGene:Hs.55999
Function	Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Protein Families	NK-3 homeobox family
Tissue Specificity	Highly expressed in the prostate and, at a lower level, in the testis.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC, IHC

Description

ELISA ; IHC, IHC ; ELISA, ELISA ; IHC

Dilution

IHC	1:50-1:100

Tested Application

ELISA,IHC;IHC:1:50-1:100

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557729	CSB-PA143729	100ul	$297		Add to Cart

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