Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.Mao M., Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998).Loeffen J., J. Inherit. Metab. Dis. 22:19-28(1999).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human NDUFS5.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Mao M., Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998). Loeffen J., J. Inherit. Metab. Dis. 22:19-28(1999).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total NDUFS5 protein.
Subcellular Location
Mitochondrion inner membrane, Peripheral membrane protein, Mitochondrion intermembrane space
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Pathway
Oxidative Phosphorylation
Protein Families
Complex I NDUFS5 subunit family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.