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Home / Primary Antibodies / IHC Antibodies

MTERF1 Antibody

SKU : BHA10559563

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA697477
Alternative Names	MGC131634; mitochondrial transcription termination factor 1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity.Fernandez-Silva P., EMBO J. 16:1066-1079(1997).Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.Hillier L.W., Nature 424:157-164(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human MTERF.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity. Fernandez-Silva P., EMBO J. 16:1066-1079(1997). Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. Hillier L.W., Nature 424:157-164(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MTERF protein.
Subcellular Location	Mitochondrion

Uniprot	Q99551
Database Links	HGNC:21463 OMIM:602318 KEGG:hsa:7978 STRING:9606.ENSP00000248643 UniGene:Hs.532216
Function	Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand.
Protein Families	MTERF family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559563	CSB-PA697477	100ul	$297		Add to Cart

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