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Home / Primary Antibodies / IHC Antibodies

Histone H2B Antibody

SKU : BHA10559837

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA013868
Alternative Names	Histone H2B type 1-H; H2B.j; H2B/j; HIST1H2BH; H2BFJ
Categories	Primary Antibodies
Clonality	polyclonal
Description	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Albig W., Genomics 40:314-322(1997).Marzluff W.F., Genomics 80:487-498(2002).Mungall A.J., Nature 425:805-811(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human Histone H2B.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Albig W., Genomics 40:314-322(1997). Marzluff W.F., Genomics 80:487-498(2002). Mungall A.J., Nature 425:805-811(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total Histone H2B protein.
Subcellular Location	Nucleus, Chromosome

Uniprot	Q93079
Database Links	HGNC:4755 OMIM:602806 KEGG:hsa:8345 STRING:9606.ENSP00000348706 UniGene:Hs.247815
Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Families	Histone H2B family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF, WB ; ELISA ; IHC ; IF

Dilution

WB	1:500-1:3000
IHC	1:50-1:100
IF	1:100-1:500

Tested Application

ELISA,WB,IHC,IF;WB:1:500-1:3000,IHC:1:50-1:100,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559837	CSB-PA013868	100ul	$297		Add to Cart

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