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Home / Primary Antibodies / IHC Antibodies

GNAL Antibody

SKU : BHA10559515

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA111285
Alternative Names	adenylate cyclase-stimulating G alpha protein; olfactory type; guanine nucleotide-binding protein G(olf) alpha;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.Zigman J.M., Endocrinology 133:2508-2514(1993).Vuoristo J.T., Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.Puhl H.L. III, Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human GNAL.
Involvement In Disease	Dystonia 25 (DYT25)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters. Zigman J.M., Endocrinology 133:2508-2514(1993). Vuoristo J.T., Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases. Puhl H.L. III, Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GNAL protein.

Uniprot	P38405
Database Links	HGNC:4388 OMIM:139312 KEGG:hsa:2774 STRING:9606.ENSP00000334051 UniGene:Hs.136295
Function	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
Pathway	Calcium signaling pathway
Protein Families	G-alpha family, G(s) subfamily
Tissue Specificity	Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559515	CSB-PA111285	100ul	$297		Add to Cart

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