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Home / Primary Antibodies / IHC Antibodies

GK Antibody

SKU : BHA10559591

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA115735
Alternative Names	GK1; GKD
Categories	Primary Antibodies
Clonality	polyclonal
Description	The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host	Rabbit
Immunogen	Fusion protein corresponding to a region derived from internal residues of Human glycerol kinase
Involvement In Disease	Glycerol kinase deficiency (GKD)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GK protein.
Subcellular Location	Mitochondrion outer membrane, Peripheral membrane protein, Cytoplasmic side, Cytoplasm

Uniprot	P32189
Database Links	HGNC:4289 OMIM:300474 KEGG:hsa:2710 UniGene:Hs.1466
Function	Key enzyme in the regulation of glycerol uptake and metabolism.
Pathway	PPAR signaling pathway
Protein Families	FGGY kinase family
Tissue Specificity	Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.

Buffer	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Form	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Format	liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:50-1:100

Tested Application

ELISA,IHC;IHC:1:50-1:100

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559591	CSB-PA115735	100ul	$297		Add to Cart

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