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Home / Primary Antibodies / IHC Antibodies

F11R Antibody

SKU : BHA10557192

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA007917KA01HU
Alternative Names	F11R;CD321;JAM;JAM-1;JAM-A;JAM1;JAMA;JCAM;KAT;PAM-1
Categories	Primary Antibodies
Description	Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5 alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Hgnc	14685, 14685
Host	Rabbit
Immunogen	Recombinant protein of human F11R
Intended Use	For research use only. Not for human, diagnostic or therapeutic use.
Isotype	IgG
Mgi	1321398, 1321398
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5 alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Size	100μl(100μg)
Species	Homo Sapiens (Human), Homo Sapiens (Human)
Subcellular Location	Cell junction, tight junction, Cell membrane, Single-pass type I membrane protein

Rgd	621842, 621842
Target Details	Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5 alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Uniprot	Q9Y624
Database Links	HGNC:14685 OMIM:605721 KEGG:hsa:50848 STRING:9606.ENSP00000289779 UniGene:Hs.517293
Function	Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3, Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3
Pathway	Leukocyte transendothelial migration, Leukocyte transendothelial migration
Protein Families	Immunoglobulin superfamily
Tissue Specificity	Expressed in endothelium, epithelium and leukocytes (at protein level).

Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Format	liquid
Purification	Affinity purification
Purity	Affinity purification
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:2000
IHC	1:50-1:200

Tested Application

ELISA,WB,IHC;WB:1:500-1:2000,IHC:1:50-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557192	CSB-PA007917KA01HU	100μl	$387.33		Add to Cart

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