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Home / Primary Antibodies / IHC Antibodies

ERCC1 mouse mAb(PT0756)

SKU : BHA12102069

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Mfr.No.	BT-MCA0573
Alternative Names	DNA excision repair protein ERCC-1
Categories	Primary Antibodies
Clonality	monoclonal
Description	PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis. In addition to caspases, other proteases like calpains, cathepsins, granzymes and matrix metalloproteinases (MMPs) have also been reported to cleave PARP1 and gave rise to fragments ranging from 42-89-kD. This antibody was generated against the N-terminal region of human PARP1 and it recognizes the full-length as well as the cleavage of the PARP1.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Host	Mouse(Mu)
Immunogen	Synthesized peptide derived from human ERCC1
Isotype	IgG1
Reactivity	Human
Regulatory	RUO

Weight	1014aa,113 kDa

Concentration	1 mg/ml
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Store at 4°C for a month, for one year store at -20°C. When reconstituted in sterile pH 7.4 0.01 M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-20°C. Avoid repeated freeze/thaw cycles.
Storage Stability	-20°C/1 year

Applications	IF, WB
Description	WB ; IP ; IF ; IHC ; ELISA
Dilution	WB 1:500-2000，IF 1:100-300

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SKU	Supplier No.	Size	Your price	Quantity
BHA12102069	BT-MCA0573	100µl	$226		Add to Cart
BHA12102069	BT-MCA0573	50µl	$110.45		Add to Cart
BHA12102069	BT-MCA0573	20µl	$69.16		Add to Cart

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