Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival By similarity. HAMAP-Rule MF_00318RH Stead, J. Neurosci., Dec 1991; 11: 3809.A. Koenig, Vet. Pathol., Jul 2001; 38: 427. Samrad Mehrabi, Chest Meeting Abstracts, Oct 2005; 128: 358S. G Paone, Eur. Respir. J., Jul 1995; 8: 1136 - 1140.
Host
Rabbit
Immunogen
Synthesized peptide derived from Human NSE.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival By similarity. HAMAP-Rule MF_00318
RH Stead, J. Neurosci., Dec 1991; 11: 3809. A. Koenig, Vet. Pathol., Jul 2001; 38: 427. Samrad Mehrabi, Chest Meeting Abstracts, Oct 2005; 128: 358S. G Paone, Eur. Respir. J., Jul 1995; 8: 1136 - 1140.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total NSE protein.
Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).
Pathway
HIF-1 signaling pathway
Protein Families
Enolase family
Tissue Specificity
The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.