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Home / Primary Antibodies / IHC Antibodies

ELOVL5 Antibody

SKU : BHA10559505

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA870663
Alternative Names	Elongation of very long chain fatty acids protein 5; ELOV5; ELOVL2; hELO1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.Leonard A.E., Biochem. J. 350:765-770(2000).Suzuki T., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.Wiemann S., Genome Res. 11:422-435(2001).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human ELOVL5.
Involvement In Disease	Spinocerebellar ataxia 38 (SCA38)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. Leonard A.E., Biochem. J. 350:765-770(2000). Suzuki T., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases. Wiemann S., Genome Res. 11:422-435(2001).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ELOVL5 protein.
Subcellular Location	Endoplasmic reticulum membrane, Multi-pass membrane protein, Cell projection, dendrite

Uniprot	Q9NYP7
Database Links	HGNC:21308 OMIM:611805 KEGG:hsa:60481 UniGene:Hs.520189
Function	Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18
Protein Families	ELO family, ELOVL5 subfamily
Tissue Specificity	Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. Expressed in the cerebellum.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:3000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559505	CSB-PA870663	100ul	$297		Add to Cart

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