May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle.Inoguchi K., J. Biochem. 117:137-146(1995).Khaleduzzaman M., Genomics 45:304-312(1997).Mungall A.J., Nature 425:805-811(2003).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human Collagen XIX α1.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle.
Inoguchi K., J. Biochem. 117:137-146(1995). Khaleduzzaman M., Genomics 45:304-312(1997). Mungall A.J., Nature 425:805-811(2003).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Collagen XIX α1 protein.
May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle.
Protein Families
Fibril-associated collagens with interrupted helices (FACIT) family
Tissue Specificity
Localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.