Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.Shimoyama Y., Biochem. J. 349:159-167(2000).The MGC Project Team, Genome Res. 14:2121-2127(2004).Tanihara H., Cell Adhes. Commun. 2:15-26(1994).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human CDH8.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Shimoyama Y., Biochem. J. 349:159-167(2000). The MGC Project Team, Genome Res. 14:2121-2127(2004). Tanihara H., Cell Adhes. Commun. 2:15-26(1994).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CDH8 protein.
Subcellular Location
Cell membrane, Single-pass type I membrane protein
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Tissue Specificity
Mainly expressed in brain. Found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.