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Home / Primary Antibodies / IHC Antibodies

CD81 Monoclonal Antibody

SKU : BHA10560914

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA0049601A0m
Alternative Names	CD81 CD81 Antigen (Target Of Antiproliferative Antibody 1) 26 KDa Cell Surface Protein TAPA-1
Categories	Primary Antibodies
Clonality	monoclonal
Description	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspaninfamily. Most of these members are cell-surface proteins that are characterized by the presence of fourhydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of celldevelopment, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is knownto complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance.Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region andthus it is a candidate gene for malignancies.
Host	Mouse
Immunogen	Recombinant Human CD81 Protein
Involvement In Disease	Immunodeficiency, common variable, 6 (CVID6)
Raised In	mouse
Reactivity	Human
Regulatory	RUO
Relevance	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspaninfamily. Most of these members are cell-surface proteins that are characterized by the presence of fourhydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of celldevelopment, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is knownto complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance.Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region andthus it is a candidate gene for malignancies.
Species	Homo Sapiens (Human)
Specificity	specific for human CD81 denatured and native forms.
Subcellular Location	Basolateral cell membrane, Multi-pass membrane protein

Uniprot	P60033
Gene Name	CD81
Clone No	2E11E5
Database Links	HGNC:1701 OMIM:186845 KEGG:hsa:975 STRING:9606.ENSP00000263645 UniGene:Hs.54457
Function	May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV.; FUNCTION
Pathway	B cell receptor signaling pathway
Protein Families	Tetraspanin (TM4SF) family
Tissue Specificity	Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Description	specific for human CD81 denatured and native forms.
Form	liquid
Format	liquid
Purification	>95%,protein G purifed
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:50-1:500

Tested Application

ELISA,IHC;Recommended dilution:IHC:1:50-1:500

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560914	CSB-MA0049601A0m	100ug	$350		Add to Cart
BHA10560914	CSB-MA0049601A0m	50ug	$210		Add to Cart

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