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Home / Primary Antibodies / IHC Antibodies

ATP6V0D1 Antibody

SKU : BHA10520703

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA002390ESR1HU
Alternative Names	V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1), ATP6V0D1, ATP6D VPATPD
Categories	Primary Antibodies
Clonality	polyclonal
Description	Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity).
Host	Rabbit
Immunogen	Recombinant Human V-type proton ATPase subunit d 1 protein (1-351AA)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity).
Species	Homo Sapiens (Human)
Subcellular Location	Membrane, Peripheral membrane protein, Cytoplasmic side

Uniprot	P61421
Gene Id	9114
Database Links	HGNC:13724 OMIM:607028 KEGG:hsa:9114 STRING:9606.ENSP00000290949 UniGene:Hs.106876
Function	Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation
Pathway	Oxidative Phosphorylation Synaptic vesicle cycle
Protein Families	V-ATPase V0D/AC39 subunit family
Research Area	Signal Transduction
Tissue Specificity	Ubiquitous.
Weight	40kDa

Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form	Liquid
Format	Liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications

ELISA, IHC

Description

ELISA ; IHC, IHC ; ELISA

Dilution

IHC	1:20-1:200

Tested Application

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10520703	CSB-PA002390ESR1HU	100ul	$299		Add to Cart
BHA10520703	CSB-PA002390ESR1HU	50ul	$166		Add to Cart

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