The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y.Franco B., Cell 81:15-25(1995).Urbitsch P., DNA Cell Biol. 19:765-773(2000).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ARSD.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y.
Franco B., Cell 81:15-25(1995). Urbitsch P., DNA Cell Biol. 19:765-773(2000).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ARSD protein