α-methylacyl-CoA racemase (AMACR), an enzyme localized in peroxisomes and mitochondria, is involved in the β-oxidation of branched-chain fatty acids and fatty acid derivatives. AMACR has been reported to be a biomarker for prostate cancer. The expression of AMACR is also related to other types of cancers such as hepatocellular carcinoma, noninvasive bladder cancer, colorectal cancer and gastric adenocarcinoma.
α-methylacyl-CoA racemase (AMACR), an enzyme localized in peroxisomes and mitochondria, is involved in the β-oxidation of branched-chain fatty acids and fatty acid derivatives. AMACR has been reported to be a biomarker for prostate cancer. The expression of AMACR is also related to other types of cancers such as hepatocellular carcinoma, noninvasive bladder cancer, colorectal cancer and gastric adenocarcinoma.
Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers.
Protein Families
CaiB/BaiF CoA-transferase family
Weight
43,860 Da
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Format
liquid
Purification
Affinity purification
Purity
Affinity purification
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer
Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.