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Home / Primary Antibodies / IHC Antibodies

AF647 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]

SKU : BHA10327448

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1132UM
Background	CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-y activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-y, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
Categories	Primary Antibodies;Primary Antibodies///Flow Cytomerty(FACS)
Clonality	Monoclonal
Host	Rat
Isotype	Rat IgG2b, k
Reactivity	Mouse
Synonyms	B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1

Antigen	CD274, PD-L1
Swissprot	Q9EP73
Clone No	10F.9G2

Buffer	PBS with 0.05% Proclin300, 1% BSA
Concentration	0.5 mg/mL
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM

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SKU	Supplier No.	Size	Your price	Quantity
BHA10327448	E-AB-F1132UM	25ug	$80		Add to Cart
BHA10327448	E-AB-F1132UM	50ug	$145		Add to Cart
BHA10327448	E-AB-F1132UM	100ug	$220		Add to Cart
BHA10327448	E-AB-F1132UM	200ug	$350		Add to Cart

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