ABC transporter 7 protein; ABC7; Anemia; sideroblastic; with spinocerebellar ataxia
Categories
Primary Antibodies
Clonality
polyclonal
Description
Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.Bekri S., Blood 96:3256-3264(2000).Ross M.T., Nature 434:325-337(2005).Maguire A., Br. J. Haematol. 115:910-917(2001).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ABCB7.
Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
Bekri S., Blood 96:3256-3264(2000). Ross M.T., Nature 434:325-337(2005). Maguire A., Br. J. Haematol. 115:910-917(2001).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ABCB7 protein.
Subcellular Location
Mitochondrion inner membrane, Multi-pass membrane protein
Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
Protein Families
ABC transporter superfamily, ABCB family, Heavy Metal importer (TC 3.A.1.210) subfamily
Weight
78,160 Da
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.