2-hydroxyisobutyryl-HIST1H3A (K18) Antibody

Mfr.No.	CSB-PA010418OA18hibHU
Alternative Names	Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l), HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J, H3FA; H3FL; H3FC; H3FB; H3FD; H3FI; H3FH; H3FK; H3FF; H3FJ
Categories	Primary Antibodies
Clonality	polyclonal
Description	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Host	Rabbit
Immunogen	Peptide sequence around site of 2-hydroxyisobutyryl-Lys (18) derived from Human Histone H3
Involvement In Disease	Glioma (GLM)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human, Rat
Regulatory	RUO
Relevance	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus, Chromosome

Uniprot	P68431
Gene Id	8350
Database Links	HGNC:4766 OMIM:137800 KEGG:hsa:8350 STRING:9606.ENSP00000444823 UniGene:Hs.132854
Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Families	Histone H3 family
Research Area	Epigenetics and Nuclear Signaling
Weight	15,404 Da

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Format	Liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF, WB ; ELISA ; ICC ; IF

Dilution

WB	1:500-1:5000
IHC	1:200-1:500
IF	1:50-1:200

Tested Application

ELISA, WB, ICC, IF; Recommended dilution: WB:1:500-1:2000, ICC:1:200-1:500, IF:1:50-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10535920	CSB-PA010418OA18hibHU	100ul	$319		Add to Cart
BHA10535920	CSB-PA010418OA18hibHU	50ul	$175		Add to Cart

2-hydroxyisobutyryl-HIST1H3A (K18) Antibody

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