B cell lineage specific activator ; BSAP ; EBB-1 ; KLP ; Paired box 5
Categories
Primary Antibodies
Cellular Localization
Nucleus
Chromosome Location
9p13.2
Clonality
monoclonal
Description
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
Host
Mouse
Immunogen
Recombinant full-length human PAX5 protein
Isotype
IgG1
Positive Control
DAUDI or Ramos Cells. Tonsil, spleen, Lymph Node or Colon Carcinoma.
Reactivity
Human
Recombinant
TRUE
Regulatory
RUO
Species
Homo Sapiens (Human)
Swissprot
Q02548
Gene Id
5079
Clone No
rPAX5, 2060
Symbol
PAX5
Weight
42kDa
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Applications
IP, WB, IHC-F
Description
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., IP ; WB ; IHC-F
Dilution
Immunoprecipitation
2-4μg/mg protein
Western Blotting
0.5-1.0μg/ml
Immunohistology (Formalin-fixed)
0.5-1μg/ml for 30 min at RT
No Description Available.
No Description Available.
Reviews of Anti-undefined Antibody rPAX5,2060 Unconjugated BHA10208280