Anti-undefined Antibody KRT15,2103R Unconjugated BHA10208177

Mfr.No.	3866-RBM3-P1ABX
Alternative Names	CK15 ; Cytokeratin 15 ; K1CO ; Ka15 ; Keratin 15 basic ; Keratin 15 beta ; Keratin complex 1 acidic gene 15 ; Keratin type I cytoskeletal 15 ; KRT15 ; KRTB ; KRTL15 ; Type I cytoskeletal 15 ; Type I keratin Ka15
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	17q21.2
Clonality	monoclonal
Description	Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.
Host	Rabbit
Immunogen	Recombinant full-length of human KRT15 protein
Isotype	IgG
Positive Control	A431 cells. Skin or Colon
Reactivity	Human, Rat, Cow
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P19012
Gene Id	3866
Clone No	KRT15, 2103R
Symbol	KRT15
Weight	52kDa

Buffer	200μg/ml of Ab purified by Protein A Column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

IHC-Ff

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., IHC-Ff

Dilution

Immunohistology (Frozen & formalin-fixed)

0.5-1.0μg/ml for 30 min at RT

No Description Available.

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208177	3866-RBM3-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody KRT15,2103R Unconjugated BHA10208177

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