Anti-Cytokeratin, Basic (Type II or HMW) Antibody BHA10207711

Mfr.No.	MSM5X-257-P1ABX
Alternative Names	KRT2B ; KRT2P ; HUMCYT2A ; Keratin, type II Cytoskeletal 2 oral ; K76 ; Keratin 2p (K2P) ; Keratin-76 ; Cytokeratin-2P (CK-2P ; Type-II Keratin Kb9
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	12q13.13
Clonality	Monoclonal
Description	This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50ā€™, 48, 46, 45, and 40kDa. This MAb recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
Host	Mouse
Immunogen	Human epidermal keratin
Positive Control	Skin, Adenocarcinomas
Reactivity	Human, Monkey, Cow, Dog, Rabbit, Mouse, Rat, Chicken
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q01546
Uniprot	654392
Gene Id	51350

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
WB	0.5-1μg/ml f
IHC-F	0.25-0.5μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10207711	MSM5X-257-P1ABX	100µg	$393.20		Add to Cart

Anti-Cytokeratin, Basic (Type II or HMW) Antibody BHA10207711

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