Anti-Testosterone Antibody BHA10207109

Mfr.No.	MSM1-250-P1ABX
Alternative Names	17β-Hydroxy-3-oxo-4-androstene ; 17β-Hydroxy-4-androsten-3-one ; 4-Androsten-17β-ol-3-one ; trans-Testosterone
Categories	Primary Antibodies
Cellular Localization	Secreted, Cytoplasmic
Clonality	monoclonal
Description	This MAb is highly specific to testosterone. Its affinity constant for testosterone is ~1010M-1. In competitive binding immunoassay, it reacts with testosterone 100%, 11-beta-hydroxy testosterone 3.3%, 17-alpha-methyl testosterone <0.1%, 5-alpha DHT 0.8%, estradiol <0.1% and progesterone <0.1%. Testosterone, a steroid hormone from the androgen group, is derived from cholesterol. Testosterone is primarily secreted in the testes, but the ovaries and adrenal glands also produce smaller amounts. It is the principal male sex hormone and is responsible for the maturation of sex organs and the development of male secondary sex characteristics. The hormone is also involved in the growth of muscle mass and increases bone density and maturation. It functions by activating the androgen receptor and converting to estradiol and activation of estrogen receptors. Testosterone has been employed therapeutically to treat many conditions including infertility, lack of libido, osteoporosis, height growth and bone marrow stimulation. Anti-testosterone antibody may also prove useful in identification of testicular tumors arising from interstitial cells.
Host	Mouse
Immunogen	Testosterone 3 CMO conjugated to BSA
Positive Control	All species
Reactivity	Interstitial or Leydid cells
Recombinant	FALSE
Regulatory	RUO

Swissprot	Not Applicable
Uniprot	Not Applicable
Gene Id	Not Applicable

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

ELISA, RIA, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., ELISA ; RIA ; IHC-F

Dilution

ELISA	For coating, order Ab without BSA
RIA
IHC-F	0.25-0.5μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10207109	MSM1-250-P1ABX	100µg	$393.20		Add to Cart

Anti-Testosterone Antibody BHA10207109

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