Anti-CD30 / TNFRSF8 Antibody BHA10206485

Mfr.No.	943-MSM4-CS0
Alternative Names	CD30L receptor ; Cytokine receptor CD30 ; Ki-1 antigen ; Lymphocyte activation antigen CD30 ; Tumor necrosis factor receptor superfamily member 8 (TNFRSF8)
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	1p36.22
Clonality	Monoclonal
Description	Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkinā€™s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Host	Mouse
Immunogen	Co cell line established from a patient with Hodgkin’s disease of T-cell lineage (Ber-H2); human CD30 recombinant protein (CD30/412)
Positive Control	Hodgkin’s lymphoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P28908
Uniprot	1314
Gene Id	943

Buffer	Tissue culture supernatant with 0.05% Azide. Contact us if you require it in a different format.
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Culture Supernatant

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	5-10μl/million cells in 0.1ml
IF	1:50-1:100
IHC-F	1:100-1:200 for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206485	943-MSM4-CS0	0.1ml	$204.67		Add to Cart
BHA10206485	943-MSM4-CS0	0.5µg	$393.20		Add to Cart

Anti-CD30 / TNFRSF8 Antibody BHA10206485

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