Anti-CD8A Antibody BHA10206245

Mfr.No.	925-MSM1-P0
Alternative Names	CD8 antigen ; alpha polypeptide (p32) ; T8/Leu-2 T-lymphocyte differentiation antigen ; Ly3 ; LYT3 ; MAL ; T-cell surface glycoprotein CD8 alpha chain
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	2p11.2
Clonality	Monoclonal
Description	CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α/β) or as a homodimer (CD8 α/α). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Host	Mouse
Immunogen	Human CD8 recombinant protein
Positive Control	HuT78 or hPBL. Tonsil
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Antigen	CD8A
Swissprot	P01732
Uniprot	85258
Gene Id	925

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206245	925-MSM1-P0	20µg	$204.67		Add to Cart
BHA10206245	925-MSM1-P0	100µg	$393.20		Add to Cart

Anti-CD8A Antibody BHA10206245

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