Anti-Macrophage L1 Protein Antibody BHA10204804

Mfr.No.	6279-MSM1-P1ABX
Alternative Names	60B8AG ; Calgranulin A (CAGA) ; Calgranulin B (CAGB) ; Calprotectin L1L subunit ; Chemotactic cytokine CP-10 ; Cystic fibrosis antigen (CFAG) ; Leukocyte L1 complex light chain ; L1Ag ; Macrophage L1 protein Calprotectin ; Migration inhibitory factor related protein 8
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	1q21
Clonality	Monoclonal
Description	Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupfferā€™s cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
Host	Mouse
Immunogen	Affinity purified monocyte membrane preparation
Isotype	IgG1 Kappa
Positive Control	Tonsil, lymph node, or spleen
Reactivity	Human, Baboon, Monkey, Cow, Pig, Goat, Horse, Cat, Dog, Rabbit, Guinea pig, Rat, Mouse
Recombinant	FALSE
Regulatory	RUO

Swissprot	P05109; P06702
Uniprot	416073; 112405
Gene Id	6279;6280

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204804	6279-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-Macrophage L1 Protein Antibody BHA10204804

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