Anti-CD45RA Antibody BHA10204457

Mfr.No.	5788-MSM14-P1ABX
Alternative Names	B220 ; CD45R ; GP180 ; Leukocyte common antigen (LCA) ; Loc ; Ly-5 ; Lyt-4 ; Protein tyrosine phosphatase receptor type C (PTPRC) ; Receptor-type tyrosine-protein phosphatase C ; T200 glycoprotein
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	1q31.3
Clonality	Monoclonal
Description	Recognizes a protein of 205kDa-220kDa, identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).
Host	Mouse
Immunogen	Stimulated human leukocytes
Isotype	IgG2a Kappa
Positive Control	Daudi, Raji, IM9 and human lymphocytes. Human lymph nodes and tonsils.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P08575
Uniprot	654514
Gene Id	5788

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204457	5788-MSM14-P1ABX	100µg	$393.20		Add to Cart

Anti-CD45RA Antibody BHA10204457

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