Anti-Beta-2 Microglobulin Antibody BHA10204361

Mfr.No.	567-MSM2X-P1ABX
Alternative Names	B2M ; Beta 2 microglobin ; Beta 2 microglobulin ; Beta chain of MHC class I molecules ; Beta-2-microglobulin form pI 5.3 ; Hdcma22p
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Extracellular(secreted)
Chromosome Location	15q21-q22.2
Clonality	Monoclonal
Description	Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
Host	Mouse
Immunogen	Full length recombinant human B2M protein
Isotype	IgG1 Kappa
Positive Control	HL-60 or HeLa cells. Melanomas and Lymphoma. Carcinoma of Stomach, Cervix, Endometrial, Kidney or Colon.
Reactivity	Human, non-human primates
Recombinant	FALSE
Regulatory	RUO

Swissprot	P61769
Uniprot	534255
Gene Id	567

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204361	567-MSM2X-P1ABX	100µg	$393.20		Add to Cart

Anti-Beta-2 Microglobulin Antibody BHA10204361

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