Anti-PDCD1 / PD1 / CD279 (Programmed Cell Death 1) Antibody BHA10203977

Mfr.No.	5133-MSM1-P1ABX
Alternative Names	CD279 ; hPD-1 ; hSLE1 ; PD1 ; PDCD1 ; Programmed Cell Death Protein 1 ; Protein PD-1 ; SLEB2 ; Systemic lupus erythematosus susceptibility 2
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	2q37.3
Clonality	Monoclonal
Description	PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
Host	Mouse
Immunogen	Recombinant full-length human PDCD1 protein
Isotype	IgG1 Kappa
Positive Control	TY cells or Tonsil.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q15116
Uniprot	158297
Gene Id	5133

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203977	5133-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-PDCD1 / PD1 / CD279 (Programmed Cell Death 1) Antibody BHA10203977

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