Anti-MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) Antibody BHA10203170

Mfr.No.	4162-MSM2-P0
Alternative Names	Cell Surface Glycoprotein MUC18 ; Cell Surface Glycoprotein P1H12 ; Gicerin ; Melanoma Adhesion Molecule (MCAM) ; Melanoma Associated Glycoprotein MUC18 ; Melanoma Cell Adhesion Molecule ; Melanoma-associated Antigen A32 ; Mel-CAM ; S-endo 1 Endothelial-associated Antigen ; Sendo1
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	11q23.3
Clonality	Monoclonal
Description	The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Host	Mouse
Immunogen	Recombinant human MCAM protein
Isotype	IgG1 Kappa
Positive Control	A-375, HUV-EC or HeLa Cells. Tonsil or Melanoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P43121
Uniprot	599039
Gene Id	4162

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1.0μg/ml
IHC-F	0.5-1.0μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203170	4162-MSM2-P0	20µg	$204.67		Add to Cart
BHA10203170	4162-MSM2-P0	100µg	$393.20		Add to Cart

Anti-MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) Antibody BHA10203170

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