Anti-Cytokeratin 14 (KRT14) Antibody BHA10202797

Mfr.No.	3861-MSM1X-P0
Alternative Names	CK-14 ; Dowling Meara ; ebs3 ; ebs4 ; Epidermolysis Bullosa Simplex ; k14 ; Keratin 14 ; Keratin Type I Cytoskeletal 14 ; Koebner ; krt14
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	17q21.2
Clonality	Monoclonal
Description	Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
Host	Mouse
Immunogen	A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14.
Isotype	IgG3
Positive Control	A431 cells. Skin or Squamous cell carcinoma
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P02533
Uniprot	6545380
Gene Id	3861

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	0.5-1.0μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202797	3861-MSM1X-P0	20µg	$204.67		Add to Cart
BHA10202797	3861-MSM1X-P0	100µg	$393.20		Add to Cart

Anti-Cytokeratin 14 (KRT14) Antibody BHA10202797

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