Anti-Androgen Receptor Antibody BHA10202442

Mfr.No.	367-MSM2-P1ABX
Alternative Names	AIS ; Dihydrotestosterone receptor (DHTR) ; HUMARA ; HYSP1 ; Kennedy disease (KD) ; Nuclear receptor subfamily 3 group C member 4 (NR3C4) ; SMAX1 ; Spinal and bulbar muscular atrophy (SBMA) ; Testicular Feminization (TFM)
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	Xq12
Clonality	Monoclonal
Description	Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This MAb is superb for staining of formalin/paraffin tissues.
Host	Mouse
Immunogen	Human DHTR recombinant protein fragment; aa151-350 (exact sequence is proprietary)
Isotype	IgG1 Kappa
Positive Control	LNCap cells or Prostate carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P10275
Uniprot	496240
Gene Id	367

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202442	367-MSM2-P1ABX	100µg	$393.20		Add to Cart

Anti-Androgen Receptor Antibody BHA10202442

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