Anti-Insulin / IRDN Antibody BHA10202421

Mfr.No.	3630-MSM4-P1ABX
Alternative Names	IDDM2, ILPR, IRDN, MODY10, Proinsulin
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	11p15.5
Clonality	Monoclonal
Description	Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Host	Mouse
Immunogen	Recombinant INS protein
Isotype	IgG1 Kappa
Positive Control	MIA PaCa-2 cells or Pancreas
Reactivity	Human, Cow, Mouse, Rat, Pig
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01308
Uniprot	272259
Gene Id	3630

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	0.1-0.2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202421	3630-MSM4-P1ABX	100µg	$393.20		Add to Cart

Anti-Insulin / IRDN Antibody BHA10202421

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