Anti-Ferritin, Light Chain (FTL) Antibody BHA10201351

Mfr.No.	2512-MSM1-P1ABX
Alternative Names	Ferritin L chain ; Ferritin L subunit ; Ferritin light chain ; Ferritin light polypeptide ; FTL ; LFTD ; NBIA3
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	19q13.33
Clonality	Monoclonal
Description	Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
Host	Mouse
Immunogen	Recombinant human FTL protein fragment (aa 38-165) (exact sequence is proprietary)
Isotype	IgG2b
Positive Control	HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P02792
Uniprot	433670
Gene Id	2512

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution