Anti-Fibronectin Antibody BHA10201224

Mfr.No.	2335-MSM2X-P1ABX
Alternative Names	Cold insoluble globulin (CIG) ; FINC ; FN1 ; FNZ ; GFND ; GFND2 ; LETS ; Migration stimulating factor (MSF) ; Ugl-Y3
Categories	Primary Antibodies
Cellular Localization	Connective tissue matrix
Chromosome Location	2q35
Clonality	Monoclonal
Description	Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.
Host	Mouse
Immunogen	T-cell lymphoma biopsy
Isotype	IgG1 Kappa
Positive Control	SW156 cells or Kidney
Reactivity	Human, Pig, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P02751
Uniprot	203717
Gene Id	2335

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201224	2335-MSM2X-P1ABX	100µg	$393.20		Add to Cart

Anti-Fibronectin Antibody BHA10201224

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