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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-CD21 / CR2 / C3d-Receptor / EBV-Receptor Antibody BHA10200604

SKU : BHA10200604

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NeoBiotechnologies, Inc.

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Mfr.No.	1380-MSM1-P0
Alternative Names	CD21 ; Complement C3d receptor (C3DR) ; Complement Receptor type 2 (CR2) ; CVID7 ; EBV receptor ; EBV-R ; Epstein-Barr virus receptor ; EVBR ; SLEB9
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	1q32
Clonality	Monoclonal
Description	Recognizes a protein of 140kDa, which is identified as the complement receptor 2 (CR2)/CD21. Its epitope is located in 5-8 short consensus repeats (SCRs). This MAb is highly specific to CR2 and shows no cross-reaction with CR1. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. MAb FR5A10 can be used for EBV receptor studies, interactions between B and T cells especially through CD23, human complement receptor (CR2) studies and IFN-alpha receptor studies.
Host	Mouse
Immunogen	Raji cells
Isotype	IgG1 Kappa
Positive Control	Tonsil
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P20023
Uniprot	445757
Gene Id	1380

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

FACS, IF, Func, IHC(fro)

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; Func ; IHC(fro)

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
Func	Order Ab without BSA & Azide
IHC(fro)	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200604	1380-MSM1-P0	20µg	$204.67		Add to Cart
BHA10200604	1380-MSM1-P0	100µg	$393.20		Add to Cart

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