Anti-CD35 / CR1 Antibody BHA10200595

Mfr.No.	1378-MSM1X-P1ABX
Alternative Names	C3 binding protein ; C3b/C4b receptor ; C3BR ; C4BR ; Complement Component (3b/4b) receptor 1 including Knops blood group system ; Complement receptor type 1 ; KN ; Knops blood group antigen
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	1q32.2
Clonality	Monoclonal
Description	Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein.ĀFollicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
Host	Mouse
Immunogen	Intact human monocytes
Isotype	IgG1 Kappa
Positive Control	Follicular dendritic cells (FDC) in tonsil
Reactivity	Human, Baboon, Cynomolgus Monkey, Rhesus monkey
Recombinant	FALSE
Regulatory	RUO

Swissprot	P17927
Uniprot	334019
Gene Id	1378

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200595	1378-MSM1X-P1ABX	100µg	$393.20		Add to Cart

Anti-CD35 / CR1 Antibody BHA10200595

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