Anti-CDX2 Antibody BHA10200153

Mfr.No.	1045-MSM1-P1ABX
Alternative Names	Caudal type homeobox 2 ; Caudal type homeobox transcription factor 2 ; Caudal-type homeobox protein 2 ; CDX2
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	13q12.2
Clonality	Monoclonal
Description	The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Host	Mouse
Immunogen	Recombinant human CDX2 protein fragment (aa150-249) (exact sequence is proprietary)
Isotype	IgG2a Kappa
Positive Control	HT29 cells or Colon Carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q99626
Uniprot	174249
Gene Id	1045

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

ELISA, FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., ELISA ; FACS ; IF ; IHC-F

Dilution

ELISA	Use Ab at 2-4μg/ml for coating
FACS	0.5-1μg/million cells
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200153	1045-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-CDX2 Antibody BHA10200153

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