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Home / Proteins & Peptide

Human Recombinant Beta Synuclein PFFs (Type 1)

SKU : BHP11901159

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StressMarq Biosciences Inc.

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Mfr.No.	SPR-457, SPR-457B, SPR-457C, SPR-457E
Alternative Names	14 kDa brain-specific protein aggregates, Beta-synuclein Protein Aggregates, Phosphoneuroprotein 14 Protein Aggregates, PNP14 Protein Aggregates, Sncb Protein Aggregates, Synuclein beta Protein Aggregates, SYUB_HUMAN Protein Aggregates
Cellular Localization	Cytoplasm
Certificate Of Analysis	Certified >95% pure using SDS-PAGE analysis.
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.
Scientific Background	Alzheimer s Disease (AD) is the most common neurodegenerative disease, affecting 10% of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Beta synuclein is abundant in neurofibrillary lesions of patients with Alzheimer's Disease. Beta synuclein is suggested to be an inhibitor of alpha synuclein aggregation- protecting the central nervous system from the neurotoxin effects of alpha synuclein (3).
Species	Human
Specificity	14.28 kDa
Accession Number	NP_001001502.1
Concentration	Lot/batch specific. See included datasheet.
Purification	Ion-exchange Purified
Expression System	E. coli
Biological Activity Abreviation	Active
Cite This Product	Human Recombinant Beta Synuclein Protein (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SPR-457B)
Nature	Recombinant
Other Relevant Information	For best results, sonicate immediately prior to use. Refer to the Neurodegenerative Protein Handling Instructions on our website, or on the product datasheet for further information..
Protein Length	Full length

Gross Weight (kg)	1.4
Launch Date	2019/03/18
Net Weight (g)	0.1
Swissprot	Q16143
Target Details	Beta Synuclein
Gene Id	6620
Research Area	Tangles & Tau, Neurodegeneration, Alzheimer's Disease, Parkinson's Disease, Synuclein, Neuroscience
Antigen	Beta Synuclein

Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.19.0030
Un Code For Transport	Non-hazardous
Unspsc Code	12352202
Shipping Temperature	Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
Buffer	PBS pH 7.4
Purity	>95%
Storage	-80 °C
Storage Buffer	PBS pH 7.4
Storage Temperature	-80°C

Applications	In vivo assay, In vitro assay, WB, SDS-PAGE

Reference	1. www.alz.org/alzheimers-dementia/facts-figures 2. Alzheimer, A. Über eine eigenartige Erkrankung der Hirnrinde. Allg. Z. Psychiatr. Psych.-Gerichtl. Med. 64, 146148 (1907). 3. Taschenberger G., et al. (2013) Ann Neurol. 74(1): 109-118.

Product Manual	Datasheet
SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP11901159-1	SPR-457B	100 ug	$390		Add to Cart
BHP11901159-2	SPR-457C	100 ug x2	$700		Add to Cart
BHP11901159-3	SPR-457E	100 ug x5	$1455		Add to Cart

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