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Home / Primary Antibodies / Polyclonal Antibodies

HSPA5 Antibody / GRP78 / BiP

SKU : BHA17102740

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NSJ Bioreagents

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Mfr.No.	F54266, F54266-0.05ML, F54266-0.2ML
Clonality	Polyclonal
Description	In cooperation with other chaperones, HSP70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. The HSP70s in mitochondria and the endoplasmic reticulum play an additional role by providing a driving force for protein translocation. They are involved in signal transduction pathways in cooperation with HSP90. They participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	Full length recombinant human protein was used as the immunogen for the HSPA5 Antibody.
Isotype	Ig
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No
Subcellular Location	Cytoplasmic

Antigen	GRP78
Uniprot	P11021

Format	Purified
Purification	SAS precipitation
Storage	Aliquot the HSPA5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC-P, IF, FACS
Dilution	Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:25,Immunofluorescence: 1:25,Flow cytometry: 1:25 (1x10e6 cells)

Product Manual	Data Sheet

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