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Home / Primary Antibodies / Monoclonal Antibodies

GluN1 (NR1, NMDA Receptor 1) Antibody, Clone N308/48 (SMC-410)

BHA11903697
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
Ask Merchant
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Antigen GluN1
Swissprot P35439
Accession Number NP_058706.1
Gene Id 24408
Target GluN1
Clone No S308-48
Research Area Cell Signaling, Neurotransmitter Receptors, NMDA Receptors, Glutamate Receptors, Neuroscience
Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration 1 mg/ml
Dilutions WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification Protein G Purified
Scientific Background The NMDA receptor (NMDAR), a glutamate receptor, is the predominant molecular device for controlling synaptic plasticity and memory function (1). The NMDA receptor forms a heterotetramer between two NR1 and two NR2 subunits (the subunits are also called glutamate-binding NMDA receptor subunits or GluN for short); two obligatory NR1 subunits and two regionally localized NR2 subunits. A related gene family of NR3 A and B subunits have an inhibitory effect on receptor activity. Multiple receptor isoforms with distinct brain distributions and functional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2 subunits.
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~105kDa.
Storage -20ºC
Storage Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications IHC, WB, ICC/IF
Description WB ; IHC ; ICC ; IF
Dilution WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Li F., and Tsien J.Z. (2009) New England J. Medicine. 361: 302-303.

2. Garcia-Gallo M., Renart J., Diaz-Guerra M. (2001) Biochem J. 356: 539-547.

3. Atlason P.T., Garside M.L., Meddows E., Whiting P., McIllhinney R.A.J. (2007) J Biol Chem. 282(35): 25299-25307.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11903697-1 SMC-410D Unconjugated 100 ug $337
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BHA11903697-2 SMC-410D-A390 ATTO 390 100 ug $392
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BHA11903697-3 SMC-410D-A488 ATTO 488 100 ug $391
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BHA11903697-4 SMC-410D-A594 ATTO 594 100 ug $391
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BHA11903697-5 SMC-410D-APC APC 100 ug $390
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BHA11903697-6 SMC-410D-BI Biotin 100 ug $386
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BHA11903697-7 SMC-410D-FITC FITC 100 ug $381
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BHA11903697-8 SMC-410D-HRP HRP 100 ug $377
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BHA11903697-9 SMC-410D-PCP PerCP 100 ug $390
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BHA11903697-10 SMC-410D-RPE RPE 100 ug $388
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BHA11903697-11 SMC-410S Unconjugated 12 ug $45
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