IV.3 reacts with a low affinity receptor for the Fc of IgG (Fc?RII, CD32) that is expressed on human platelets, monocytes, granulocytes and B cells. IV.3 also cross-reacts with granulocytes and monocytes from peripheral blood lymphocytes from non-human primates.
Host
Mouse
Immunogen Region
K-562 human erythromyeloblastoid leukemia cell line