CD1a Unconjugated OKT6 IgG1,k (RUO)

Mfr.No.	111501, 111503
Clonality	Monoclonal
Description	The clone OKT6, a mouse monoclonal antibody selectively recognizes 49-kDa type I transmembrane glycoprotein non-covalently associated with ?2-microglobulin known as CD1a. The CD1a glycoprotein has structural similarities to MHC class I molecule and plays important role in antigen-presenting mechanism to T-cell receptors present on NK T-cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation NK T-cells, CD1a has been implicated in thymic T cell development. CD1a has been used as a marker for DCs in a range of human tumors and the density of CD1a DC has been associated with clinical outcome in patients with lung, colon, gastric, nasopharyngeal, laryngeal and tongue carcinomas.
Host	Mouse
Immunogen Region	Human acute lymphoblastic leukemia cells
Isotype	IgG1,k
Reactivity	Human

Product Manual	Datasheet MSDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA19900006-1	111501	100 ug	$110		Add to Cart
BHA19900006-2	111503	500 ug	$390		Add to Cart