CD105 PE SN6h IgG1,k (ASR)

Mfr.No.	4125022, 4125025
Clonality	Monoclonal
Description	The clone SN6h, a mouse monoclonal antibody selectively binds to a ~95 kDa type I transmembrane homodimer glycoprotein known as CD105. It is also encoded by END (Endoglin) and belongs to the TGF-? type III receptor family. CD105 mostly expressed on vascular endothelial cells, placental syncytiotrophoblasts, mesenchymal stem cells, erythroid precursors, activated macrophages, pre-B cells, and some tumor cells and cell lines including U937 cells. CD105 works as an important regulatory component of the TGF-? receptor system. CD105 expression is increased on activated endothelium tissues undergoing angiogenesis and also in cases of wound healing or dermal inflammation. CD105 may also be involved in the solid tumor metastasis, in regulation of cytoskeletal cellular organization as well as migration.
Host	Mouse
Immunogen Region	EDG (CD105) isolated from acute lymphoblastic leukemia cells
Isotype	IgG1,k
Reactivity	Human

Product Manual	Datasheet MSDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA19900918-1	4125022	50 Test	$270		Add to Cart
BHA19900918-2	4125025	100 Test	$445		Add to Cart