Cell surface antigen MAX.3 ; hCD84 ; Hly9-beta ; Leucocyte differentiation antigen CD84 ; LY9B ; Signaling lymphocytic activation molecule 5 (SLAMF5) ; SLAM family member 5
Categories
Primary Antibodies
Cellular Localization
Cell Surface
Chromosome Location
1q24
Clonality
Monoclonal
Description
Recognizes a protein of 74kDa, identified as CD84 (Workshop V; Code A085, C057). It is expressed on mature B cells and on B-cell lines, including pre-B-cell lines, but not on plasma cell lines. Immunohistochemical studies demonstrated that CD84 strongly expressed on tissues macrophages. CD84 is also highly expressed on platelets and, at low levels on peripheral blood T cells. It is a highly N-glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation.
Host
Mouse
Immunogen
Spleen cells of a patient with hairy cell leukemia
Positive Control
Raji, HL60, THP-1, HMC-1, HEL and NAMALWA cells. Human platelets and macrophages. Human tonsil.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
Q9UIB8
Uniprot
398093
Gene Id
8832
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF
Description
Optimal dilution for a specific application should be determined., FACS ; IF
Dilution
FACS
0.5-1μg/million cells in 0.1ml
IF
0.5-1μg/ml
Reviews of Anti-CD84 / SLAMF5 Antibody BHA10205980