The retinoblastoma tumor suppressor gene, RB, encodes a protein of 110 KD that plays an important role in cell growthregulation. Retinoblastoma is an intraocular cancer of early childhood that arises from the developing retina. In asubstantial proportion of cases, susceptibility to retinoblastoma can be inherited from a parent who was previously cured ofthe tumor.
Storage
Store the probe at 2-8o C. Warm to room temperature immediately prior to use.