The MYC dual color break apart probe is two direct labeled hybrid probes and hybridized in 8q24.21 region. The probe was hybridized with the proximal end of the MYC gene, and the green dye labeled probe hybridized with the distal MYC gene.
Description
Hematological tumor
Clinical Significance
The MYC gene breaks in 5%-10% patients with diffuse large B cell lymphoma , and the survival time is shorter than that of the normal patients; the MYC gene break and the BCL2 gene break or the BCL6 gene break can be used for the diagnosis of the double strike lymphoma (DHL).