CBFB gene break apart probe uses the orange red dye to mark the 5 'end of the CBFB gene region, the CBFB gene was labeled with green dye at the 3' end, and the MLL gene break apart probe was used to detect the translocation of the 16q22 section, and all the CBFB gene rearrangements could be detected, and the missed diagnosis caused by a single fusion gene was avoided.
Description
Lymphatic hematopoietic system tumor
Clinical Significance
Most AML patients with CBFB gene CBFB gene break apart rearrangement are sensitive to chemotherapy and have better prognosis.