The MYC gene amplification probe uses orange-red dye to mark the MYC gene region, and the green dye to mark the centromeric region of chromosome 8 (CEP8). The MYC gene tagged region is located at 8q24.21 and the CEP8 probe is labeled with a specific alpha satellite sequence.
Description
Lymphatic hematopoietic system tumors
Clinical Significance
MYC gene amplification is a common phenomenon in tumors and can be seen in many malignant tumors such as breast cancer, nasopharyngeal cancer, and cervical cancer. The prognosis of breast cancer patients with MYC gene is poor.